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NMR Spectrometers in Chemistry

Bruker 400 MHz NB
“400 narrow bore”, “400NB”
1H, 13C, 31P, 19F, some X
Sample Changer
Bruker 400MHz “NEO400” 1H, 13C, 31P, 19F, X, “Prodigy Probe”, Sample Changer
Bruker 500 MHz
“500” or “B500”
1H and X, VT, kinetics, 2D
Bruker 600 MHz
1H, 19F, 13C, {15N} “cryoQCI”
Sample Changer (BBFO backup probe)
Bruker 600 MHz “NEO600”1H, 13C, 31P, 15N “cryoQNP”
(BBFO backup probe)


Spectrometer Selection

1H31P13C19F11B, 29Si and other nucleiVariable TempCOSY, HSQC, HMBC, NOESY5mm tubes with the following exceptions
400NB (autoNMR)YesYesYes (conc.)YesSome are possibleN.A.Yesgreater than 6 inches
NEO400 ("Prodigy")
Yes (low conc.)Yes (low conc.)YesYes, no 1H decouplingYes~ -40 to +120Yes (low conc.)special spinners for variable temperature
NEO600 (cryoQNP)Yes (low conc.)Yes (low conc.)Yes (low conc.)NoNo0 to 60 CelciusYes (low conc.)short J-Young tubes
B600 (cryoQCI)Yes (low conc.)NoYes (low conc.)Yes (low conc.)No0 to 60 CelsiusYes (low conc.)
500 (bbo or bbi probe)YesYes (best on bbo)Yes (conc., bbo)NoYes (bbo)-120 to +120Yesspecial spinners for variable temperature

Yes connc: requires concentrated samples
Yes (low conc.): good for dilute samples


Signal-to-noise ratios