NMR Core Laboratory
Support for the application of Nuclear Magnetic Resonance (NMR) Spectroscopy is provided by the Department of Chemistry’s NMR Facility for a variety of applications. Although many NMR active nuclei can be observed, we have extensive capabilities, including highly sensitive cryoprobes, for the detection of 1H, 2H, 13C, 15N, 19F and 31P. Gradient enhanced pulse sequences and variable sample temperature control are available for 1D and multidimensional experiments. Training and access to the facility is encouraged for the entire UNC-CH campus, other universities and colleges, and local industry.
Our six spectrometers include two 400 MHz Bruker spectrometers for standard 1D and 2D NMR, a 360 MHz Bruker spectrometer for solids and other unique samples, a Bruker 500 MHz system for advanced applications in multinuclear and reaction kinetics at extreme temperature (+/- 120 C), a Varian/Agilent 600MHz spectrometer mostly used for 1H detection and a Bruker 600 MHz spectrometer equipped with a 60 position sample changer and two cryoprobes.
ABOUT US
The NMR Core provides access to high resolution NMR spectroscopy and EPR spectroscopy and is part of the Department of Chemistry Chemical Research Instrumentation Teaching and Core Laboratories. While most users obtain training to acquire their own NMR data, samples can be submitted for automated runs (including “drop off NMR”) or run by NMR staff. We work with the NMR Cores in the School of Pharmacy and the School of Medicine to provide NMR services and expertise to the UNC Chapel Hill Department of Chemistry, the UNC Campus community and the Research Triangle area. <add picture of Marc working with students>
It is our goal to be a leading resource for small molecule NMR in the Southeastern United States.
We will accomplish this mission by:
• Facilitating NMR applications to cutting edge research
• Implementing standard and advanced NMR experiments
• Training and educating people in the acquisition of NMR data and the application of NMR spectroscopy
• Obtaining and maintaining state of the art instrumentation
SPECTROMETER SCHEDULE
|
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
Saturday |
Sunday |
AV3400 (400NB)
BBFO
BACS (60) |
9am-1pm |
RSVP time to acquire data
Short runs |
| 1pm-6pm |
| 6pm-9am |
Long runs and short runs |
NEO400
Prodigy probe
SampleXpress (60) |
9am-1pm |
In automation 24/7, RSVP to submit sample(s)
Each submission must be less than 20 minutes or maximum 4 1H 1Ds |
| 1pm-6pm |
| 6pm-9am |
Automation, long runs and short runs, extended runs by request |
AV3500
(500) |
9am-1pm |
RSVP time to acquire data
Priority for long runs (1 hour and more), short runs reserved same day |
| 1pm-6pm |
| 6pm-9am |
NEO600
CryoQNP
13C, 31P, 1H, 15N
SampleCase (24) |
9am-1pm |
In automation 24/7, RSVP to submit sample(s)
Each submission must be less than 20 minutes or
maximum 4 1H 1Ds |
| 1pm-6pm |
| 6pm-9am |
Automation, long runs and short runs, possible drop off after 7pm |
AV3600
(B600) CryoQCI 1H, 19F, 13C, 15N SampleXpress (60) |
9am-11am |
RSVP time to acquire data
Priority for long runs, short runs reserved same day |
| 11am-5pm |
| 5pm-9am |
Manual mode with occasional, drop off |