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Lauren Koval (she/her)

Doctoral student in ESE (2020-present)

*B.A. in Physics, Oberlin College

*Lauren’s research centers on evaluating health effects resulting from diverse environmental exposures. In particular, she focuses on the influence of chemical mixtures in household environments on breast cancer risk using high-throughput informatic approaches. 

Contact info: lkoval@unc.edu

Publications:

  1. Carberry CK, Koval LE, Payton A, Hartwell H, Kim YH, Smith GJ, Reif DM, Jaspers I, Gilmour MI, Rager JE. Wildfires and Extracellular Vesicles: Exosomal MicroRNAs as Mediators of Cross-Tissue Cardiopulmonary Responses to Biomass Smoke. Environ. Int. 2022 July 16. doi: 10.1016/j.envint.2022.107419. Epub ahead of print. 
  2. Roell K†, Koval LE†, Boyles R, Patlewicz G, Ring C, Rider CV, Ward-Caviness C, Reif DM, Jaspers I, Fry RC, Rager JE. Development of the inTelligence And Machine lEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research. Front. Toxicol. 2022 Jun 22. doi: 10.3389/ftox.2022.893924. Epub ahead of print.  
  3. Koval LE, Dionisio KL, Friedman KP, Isaacs KK, Rager JE. Environmental Mixtures and Breast Cancer: Identifying Co-Exposure Patterns between Understudied vs Breast Cancer-Associated Chemicals using Chemical Inventory Informatics. J Expo Sci Environ Epidemiol. 2022 Jun 16. doi: 10.1038/s41370-022-00451-8. Epub ahead of print. PMID: 35710593. 
  4. Carberry CK, Turla TM, Koval LE, Hartwell H, Fry RC, Rager JE. Chemical Mixtures in Household Environments: In Silico Predictions and In Vitro Testing of Potential Joint Action on PPARγ in Human Liver Cells. Toxics. 2022 April 19;10(5), 199. doi: 10.3390/toxics10050199 
  5. Ring C, Sipes NS, Hsieh JH, Carberry C, Koval LE, Klaren WD, Harris MA, Auerbach SS, Rager JE. Predictive modeling of biological responses in the rat liver using in vitro Tox21 bioactivity: Benefits from high-throughput toxicokinetics. Comput Toxicol. 2021 May;18:100166. PMID: 34013136; PMCID: PMC8130852.