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NMR Core Laboratory

Support for the application of Nuclear Magnetic Resonance (NMR) Spectroscopy is provided by the Department of Chemistry’s NMR Facility for a variety of applications. Although many NMR active nuclei can be observed, we have extensive capabilities, including highly sensitive cryoprobes, for the detection of 1H, 2H, 13C, 15N, 19F and 31P. Gradient enhanced pulse sequences and variable sample temperature control are available for 1D and multidimensional experiments. Training and access to the facility is encouraged for the entire UNC-CH campus, other universities and colleges, and local industry.

Student working on lab equipment.

Our six spectrometers include two 400 MHz Bruker spectrometers for standard 1D and 2D NMR (one with a broad band Prodigy cryoprobe),  a Bruker 500 MHz system for advanced applications in multinuclear and reaction kinetics at extreme temperature (+/- 120 C), two Bruker 600 MHz spectrometer equipped with a 60 position sample changer and two cryoprobes.



The NMR Core provides access to high resolution NMR spectroscopy and EPR spectroscopy and is part of the Department of Chemistry Chemical Research Instrumentation Teaching and Core Laboratories.  While most users obtain training to acquire their own NMR data, samples can be submitted for automated runs (including “drop off NMR”) or run by NMR staff.  We work with the NMR Cores in the School of Pharmacy and the School of Medicine to provide NMR services and expertise to the UNC Chapel Hill Department of Chemistry, the UNC Campus community and the Research Triangle area.  <add picture of Marc working with students>

It is our goal to be a leading resource for small molecule NMR in the Southeastern United States.

We will accomplish this mission by:

Facilitating NMR applications to cutting edge research
Implementing standard and advanced NMR experiments
Training and educating people in the acquisition of NMR data and the application of NMR spectroscopy
Obtaining and maintaining state of the art instrumentation

Post-doc position

Magnetic Resonance Post-doctoral scholar in the NMR Core Laboratory


The Magnetic Resonance Post-Doctoral Scholar in the NMR Core laboratory at UNC Department of Chemistry plays a key role in implementing and expanding the use of NMR and EPR spectroscopy in the Core. This individual will collaborate with faculty, post-docs and students in magnetic resonance as well as train users and assist with the maintenance of instrumentation. The position is designed to expand technical expertise in magnetic resonance while developing managerial skills.


The research role (50%) includes a heavy emphasis on developing standard and advanced operating procedures in NMR and/or EPR spectroscopy and sharing capabilities with students and researchers.  Training, seminars and advanced training workshops are expected along with simulations and direct consultation and collaboration with research groups. Applications include variable temperature, time resolved experiments and the monitoring of light induced chemistry. Additional applications are possible.


The laboratory management and skill development role (50%) involves working with the laboratory team to maintain a readily accessible and reliable collection of instrumentation for the acquisition of NMR data.  This includes coordinating with core staff to support high throughput runs using the sample changers on NMR spectrometers, general maintenance of spectrometers and associated magnets, diagnosing instrument issues and assisting and training users.  Additional experience in managing a major magnetic resonance laboratory.


Principal Functions:

  1. Research (50% effort): promote the use of NMR and/or EPR spectroscopy including but not limited to variable temperature and time resolved experiments through hardware, software and procedure development. The individual will work with students to adapt NMR and/or EPR to their research needs and collaborate with researchers.


  1. Laboratory Management (50% effort): work with the staff in the core to support EPR and NMR applications. Instrument maintenance including: cryogen fills, sample changers, NMR probes and EPR resonators.  Software support for EPR simulations and NMR spectroscopy.  Supporting helium recovery, training, and general lab support are expected.


Apply at the following link and specify “NMR Post-doc” in the cover letter.


For more information:

Marc ter Horst, Research Professor and NMR Core Laboratory Director, 919-843-5802

056 Caudill Labs, Department of Chemistry, CB #3290

UNC at Chapel Hill, Chapel Hill, NC  27599-3290