Iron-sensitive RNA regulation by poly C binding proteins.
Forbes K, Goda GA, Eramo GA, Breen C, Porter DF, Khavari PA, Dominguez D, Aleman MM. BioRxiv. 2024. doi: https://doi.org/10.1101/2024.10.17.618301
Coagulation and Platelet Biology at the Intersection of Health and Disease: Illustrated Capsules of the 11th Symposium on Hemostasis at the University of North Carolina.
Aleman M, Arepally GM, Baglin T, Buitrago L, Davizon-Castillo P, Dayal S, Flick MJ, Gerber G, Hisada Y, Kolev K, O’Loghlen A, Rezaie AR, Sparkenbaugh EM, Stavrou EX, Ünlü B, Vercellotti GM. Research and Practice in Thrombosis and Haemostasis. 2024 doi: https://doi.org/10.1016/j.rpth.2024.102395
Understanding species-specific and conserved RNA-protein interactions in vivo and in vitro
Harris SE, Alexis MS, Giri G, Cavazos FF, Murn J, Aleman MM, Burge CB, Dominguez D. Nature Communications, 2024, 15(article number 8400). Pubmed PMID: 39333159
Reciprocal stabilization of coagulation factor XIII-A and -B subunits determines plasma FXIII concentration.
Byrnes JR, Lee TK, Sharaby S, Campbell RA, Dobson D, Holle LA, Luo M, Kantor K, Homeister J, Aleman MM, Luyendyk JP, Kerlin BA, Dumont JB, Wolberg AS. Blood. 2024 Feb 1;143(5):444-455. Pubmed PMID: 37883802
Efanesoctocog alfa elicits functional clot formation that is indistinguishable to that of recombinant factor VIII.
Demers M*, Aleman MM*, Kistanova E, Peters R, Salas J, Seth Chhabra E. J Thromb Haemost. 2022 Apr 25. Pubmed PMID: 35466511
Quantitative profiling of adaptation to cyclin E overproduction.
Limas JC, Littlejohn AN, House AM, Kedziora KM, Mouery BL, Ma B, Fleifel D, Walens A, Aleman MM, Dominguez D, Cook JG. Life Sci Alliance. 2022 Feb 16;5(5):e202201378. Pubmed PMID: 35173014
LIN28B alters ribosomal dynamics to promote metastasis in MYNC-driven malignancy.
Missios P, Lummertz da Rocha E, Pearson DS, Philipp J, Aleman MM, Pirouz M, Farache D, Franses JW, Kubaczka C, Tsanov KM, Jha DK, Pepe-Mooney B, Powers JT, Gregory RI, Lee ASY, Dominguez D, Ting DT, Daley GQ. J Clin Invest. 2021 Nov 15;131(22):e145142. Pubmed PMID: 34779407
easyCLIP Analysis of RNA-Protein Interactions Incorporating Absolute Quantification.
Porter DF, Miao W, Yang X, Goda GA, Ji AL, Donohue LKH, Aleman MM, Dominguez D, Khavari PA. Nature Comm. 2021 12:Article number: 1569. Pubmed PMID: 33692367
Intrinsic differences between FVIIIa mimetic bispecific antibodies and FVIII prevent assignment of FVIII-equivalence.
Leksa NC, Aleman MM, Goodman AG, Rabinovich D, Peters R, Salas J. J Thromb Haemost. 2019 Jul;17(7):1044-1052. PubMed PMID: 30887655.
Assay challenges (and opportunities) with non-factor VIII therapies for Hemophilia A.
Aleman MM, Leksa NC, Peters R, Salas J. Expert Rev Mol Diagn. 2019 Jan;19(1):1-3. PubMed PMID: 30513018.
A proof-of-concept clinical study examining the NRF2 activator sulforaphane against neutrophilic airway inflammation.
Duran CG, Burbank AJ, Mills KH, Duckworth HR, Aleman MM, Kesic MJ, Peden DB, Pan Y, Zhou H, Hernandez ML. Respir Res. 2016 Jul 22;17(1):89. PubMed PMID: 27450419.
Complement Activation in Arterial and Venous Thrombosis is Mediated by Plasmin.
Foley JH, Walton BL, Aleman MM, O’Byrne AM, Lei V, Harrasser M, Foley KA, Wolberg AS, Conway EM. EBioMedicine. 2016 Mar;5:175-82. PubMed PMID: 27077125.
The IL-1 axis is associated with airway inflammation after O3 exposure in allergic asthmatic patients.
Aleman MM, Kesic MJ, Mills KH, Peden DB, Hernandez ML. J Allergy Clin Immunol. 2015 Oct;136(4):1099-101.e2. PubMed PMID: 25959670.
Cystamine preparations exhibit anticoagulant activity.
Aleman MM, Holle LA, Stember KG, Devette CI, Monroe DM, Wolberg AS. PLoS One. 2015;10(4):e0124448. PubMed PMID: 25915545.
IL-1 receptor antagonist reduces endotoxin-induced airway inflammation in healthy volunteers.
Hernandez ML, Mills K, Almond M, Todoric K, Aleman MM, Zhang H, Zhou H, Peden DB. J Allergy Clin Immunol. 2015 Feb;135(2):379-85. PubMed PMID: 25195169.
Factor XIII activity mediates red blood cell retention in venous thrombi.
Aleman MM, Byrnes JR, Wang JG, Tran R, Lam WA, Di Paola J, Mackman N, Degen JL, Flick MJ, Wolberg AS. J Clin Invest. 2014 Aug;124(8):3590-600. PubMed PMID: 24983320.
Fibrinogen and red blood cells in venous thrombosis.
Aleman MM, Walton BL, Byrnes JR, Wolberg AS. Thromb Res. 2014 May;133 Suppl 1:S38-40. Review. PubMed PMID: 24759140.
Strengths and weaknesses of a new mouse model of thrombosis induced by inferior vena cava stenosis: communication from the SSC of the ISTH.
Geddings J, Aleman MM, Wolberg A, von Brühl ML, Massberg S, Mackman N. J Thromb Haemost. 2014 Apr;12(4):571-3. PubMed PMID: 24460606.
Elevated prothrombin promotes venous, but not arterial, thrombosis in mice.
Aleman MM, Walton BL, Byrnes JR, Wang JG, Heisler MJ, Machlus KR, Cooley BC, Wolberg AS. Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):1829-36. PubMed PMID: 23723374.
Tick spit shines a light on the initiation of coagulation.
Aleman MM, Wolberg AS. Circulation. 2013 Jul 16;128(3):203-5. PubMed PMID: 23817576.
Murine models do not recapitulate the pathophysiology of age-related venous thrombosis in humans.
Cardenas JC, Aleman MM, Wang JG, Whinna HC, Wolberg AS, Church FC. J Thromb Haemost. 2013 May;11(5):990-2. PubMed PMID: 23480546.
Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer.
Wang JG, Geddings JE, Aleman MM, Cardenas JC, Chantrathammachart P, Williams JC, Kirchhofer D, Bogdanov VY, Bach RR, Rak J, Church FC, Wolberg AS, Pawlinski R, Key NS, Yeh JJ, Mackman N. Blood. 2012 Jun 7;119(23):5543-52. PubMed PMID: 22547577.
Procoagulant activity in hemostasis and thrombosis: Virchow’s triad revisited.
Wolberg AS, Aleman MM, Leiderman K, Machlus KR. Anesth Analg. 2012 Feb;114(2):275-85. Review. PubMed PMID: 22104070.
Differential contributions of monocyte- and platelet-derived microparticles towards thrombin generation and fibrin formation and stability.
Aleman MM, Gardiner C, Harrison P, Wolberg AS. J Thromb Haemost. 2011 Nov;9(11):2251-61. PubMed PMID: 21883880.
Update on venous thromboembolism: risk factors, mechanisms, and treatments.
Machlus KR, Aleman MM, Wolberg AS. Arterioscler Thromb Vasc Biol. 2011 Mar;31(3):476-8. PubMed PMID: 21325668.
Flow profoundly influences fibrin network structure: implications for fibrin formation and clot stability in haemostasis.
Campbell RA*, Aleman M*, Gray LD, Falvo MR, Wolberg AS. Thromb Haemost. 2010 Dec;104(6):1281-4. PubMed PMID: 20886193.
Influence of cellular and plasma procoagulant activity on the fibrin network.
Wolberg AS, Aleman MM. Thromb Res. 2010 Apr;125 Suppl 1:S35-7. Review. PubMed PMID: 20163831.
Caveolin-1 knockout mice have increased bone size and stiffness.
Rubin J, Schwartz Z, Boyan BD, Fan X, Case N, Sen B, Drab M, Smith D, Aleman M, Wong KL, Yao H, Jo H, Gross TS. J Bone Miner Res. 2007 Sep;22(9):1408-18. PubMed PMID: 17550335.
Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes.
San Martín A, Du P, Dikalova A, Lassègue B, Aleman M, Góngora MC, Brown K, Joseph G, Harrison DG, Taylor WR, Jo H, Griendling KK. Am J Physiol Heart Circ Physiol. 2007 May;292(5):H2073-82. PubMed PMID: 17237245.