Collaborators, research group members, and mentees of Dr. Lund have utilized data resources from the Sheps Center, CIPHR, and publicly available data to conduct research across cancer, aging, and pharmacoepidemiology. Explore below for a non-exhaustive sample of projects which group members have collaborated in and published.
Effectiveness of adjuvant FOLFOX vs 5FU/LV in adults over age 65 with stage II and III colon cancer using a novel hybrid approach
Association between Concomitant Use of Hydrochlorothiazide and Adverse Chemotherapy-Related Events among Older Women with Breast Cancer Treated with Cyclophosphamide
National Health and Aging Trends Study (NHATS) and NHATS-Medicare
The National Health and Aging Trends Study (NHATS) is sponsored by the National Institute on Aging through a cooperative agreement with the Johns Hopkins Bloomberg School of Public Health. NHATS conducts annual in-home interviews for a diverse, nationally-representative sample of Medicare beneficiaries aged 65 years and older. NHATS data are publicly available for researchers through registration on the NHATS site.
Research group members also utilize linkages to Medicare claims data for their research (NHATS-Medicare).
Medicare 20% Sample
Learn more by visiting the Sheps Center.
Translation of a claims-based frailty index from International Classification of Diseases 9th Revision to 10th Revision
Real-world on-treatment and initial treatment absolute risk differences for dabigatran vs warfarin in older US adults
MarketScan® (1% Sample and 100% Sample)
The Merative MarketScan® Commercial Claims and Encounters Database are proprietary collections of de-identified US patient data available for healthcare research. If features more than 264 million covered individuals, 37 billion service records, more than 160 contributing employers and 40 contributing health plans. Data are housed and managed by the Sheps Center for Health Services Research, where non-proprietary information on the database and access guidelines can be found.
Students enrolled in the Healthcare Databases course (EPID766/DPOP766) conduct a descriptive epidemiologic group project using a 1% sample of the MarketScan® database. Upon completion of the course, students have chosen to apply for a Data Use Agreement to utilize the full MarketScan® database to refine their course project into a published peer-reviewed manuscript.
Through the course, students learn how healthcare utilization data are generated and use databases to identify study populations and conduct epidemiologic analysis of the utilization and comparative effectiveness/safety of prescription drugs and healthcare services. Students conduct a descriptive epidemiologic group project using a 1% sample of the MarketScan® database, and may choose to refine their course project towards manuscript publication post-course completion.
Utilization of Colonoscopy Following Treatment Initiation in U.S. Commercially Insured Patients With Inflammatory Bowel Disease, 2013-2019
Adherence to endocrine therapy including ovarian suppression: A large observational cohort study of US women with early breast cancer
The Lund Research Group collaborates closely with the UNC Lineberger Cancer Center and the Sheps Center to conduct research at the intersection of pharmacoepidemiology, aging, and cancer.
CIPHR, or the Cancer Information & Population Health Resource, is a central component of the UNC Lineberger Comprehensive Cancer Center’s Outcomes Research Program. CIPHR provides a prospective data linkage between metrics of cancer incidence, mortality, and burden in North Carolina and data sources at an individual and aggregate level that describe health care, economic, social, behavioral, and environmental patterns. The CIPHR data inventory includes an innovative, comprehensive, and prospectively linked North Carolina population‐level data sets and existing linked national data sets. These data include the North Carolina Central Cancer Registry linked to administrative and claims data for a 100% sample of North Carolinians from Medicare, Medicaid, and private insurance plans, and Surveillance, Epidemiology, and End Results (SEER) program linkages with Medicare enrollment and claims (SEER‐Medicare), the Consumer Assessment of Healthcare Providers and Systems (SEER‐CAHPS), and Medicare Health Outcomes Survey (SEER‐MHOS).
Dr. Lund is a senior CIPHR investigator and faculty mentor of the CIPHR New Investigator Program. The New Investigator Program provides support and structured mentoring to UNC post‐doctoral trainees, junior faculty, and clinical fellows who propose to use multi‐payer North Carolina cancer registry linked data, SEER‐Medicare, or other surveillance or administrative data in cancer outcomes research. If you are a prospective new investigator interested in leveraging CIPHR to advance cancer outcomes research, please find program details at the CIPHR website and/or contact firstname.lastname@example.org .