Reflections on the 12th Annual Advanced Course in Diagnostics (ACDx) in Annecy, France

Posted on by cmckay1

I am writing this in the airport in Geneva waiting for my flight home from ACDx. This summer for my practicum, I had the pleasure of working with the Mérieux Foundation as they prepared for the 12th annual Advanced Course on Diagnostics (ACDx). This course brings together professionals from all over the world and different sectors, including research, clinical laboratories, policy and regulation, and biotechnology to discuss diagnostics. We had six days packed full of lectures, panel discussions, and workshops all hosted at Les Pensières in Annecy, France.

One of the many qualities that makes ACDx a special event is that it is relatively small. This year there were 25 participants, and a set of core faculty with several additional speakers who rotated throughout the week. We all stayed at Les Pensières Center for Global Health in Annecy, on the beautiful lake. This setting allowed us to build true connections, not only spending all day together learning but continuing those conversations over shared meals, walking along the lake, and exploring the town.

A scenic shot of the river and old town Annecy

The core focus throughout the week is improving equitable access to diagnostics, especially in LMICs. It was a great demonstration of global public health in action. Colleagues from around the world were discussing the barriers to access to high quality and affordable diagnostics in their respective communities, and how to collaborate to build sustainable solutions to complex problems. Throughout the week we heard from experts at WHO, Africa CDC, ASLM, NIH, FIND, UNITAID, Fondation Merieux and more covering various topics in diagnostics from emerging technologies to laboratory system strengthening, regulatory harmonization, antimicrobial resistance, social innovation for public health, public health communications about diagnostics and One Health, and the implications of climate change on diagnostics. Honestly, my head is still spinning a bit from all the great talks we heard and conversations we had. I look forward to keeping in touch with the colleagues I met this week, and I hope to return to Annecy someday soon.

-Sophie

The ACDx group participants pose for a picture outside in front of tall green trees

To learn more about ACDx, visit: https://www.fondation-merieux.org/en/events/12th-advanced-course-on-diagnostics-acdx/

My Experience Contributing to Severe Malaria Research in Uganda

Posted on by cmckay1

This is my last day in Bugoye, Uganda and as I look at the sunset over the health center framed by the foothills of the Rwenzori Mountains, I reflect on the past six weeks in this beautiful country. I have had the privilege to work on a study of pediatric severe malaria at a nearby Level IV health center for my practicum while also exploring some of the national parks and wildlife that “the pearl of Africa” has to offer. It has been a challenging and rewarding experience.

Mountains in the distance with an orange sunset in the background
A beautiful view in Bugoye, Uganda

We hit the ground running as soon as I arrived in Bugoye with work on the Severe Malaria study. Due to delays in IRB approval, data collection had not yet begun when I arrived, so I worked with the Severe Malaria team to ensure data collection forms were working properly, and to troubleshoot issues that arose when we began data collection. I’m grateful to be working with a highly motivated and friendly team, who are continuing data collection as I prepare to leave Uganda. While there were certainly challenges with starting up a new study in a new research site, the most challenging aspect of this work for me personally has been seeing the children with severe malaria when they arrived. Many children suffer from some of the worst symptoms of severe malaria upon arrival. Convulsions, changes or loss of consciousness, and severe anemia were commonplace. Some are in a truly critical state, and each instance I witnessed was heartbreaking. However, I’ve also been amazed by the miracle of modern medicine. Within 3-4 days of receiving treatment, it was not uncommon to see a young child who arrived in grave condition to be alert and playing. Seeing this incredible transformation from the dire state in which many arrive was incredibly heartening. Additionally, seeing the devastating effects of this disease up close has inspired me to continue working on this study through data analysis in the upcoming semester. This has been a transformative experience, and I could not be more grateful for all I’ve learned during my six weeks here.

I’ve also had the opportunity to explore the scenic areas that surround Bugoye. Among these incredible experiences, one day stands out as an absolute highlight – a challenging 18-kilometer (11 miles) hike that took us to a glacial lake at an elevation of 9,000 feet within the Rwenzori Mountains. Although this was a strenuous hike, we were rewarded with views of towering mountains, waterfalls, and the lake at the summit. Our guide, Michael, proved to be an invaluable companion on this hike. His extensive knowledge of the local flora and fauna enriched our understanding of the ecosystem that surrounded us. With an uncanny ability to spot even camouflaged animals, he helped us see two distinct monkey species swinging gracefully through the treetops. We even found a three-horned chameleon, a true testament to the region’s biodiversity. I also embarked on another excursion to Queen Elizabeth National Park. Here, I had the privilege of seeing chimps high in the treetops during a chimp trek. Moreover, I enjoyed a tranquil boat safari along the park’s main river, where we saw elephants, hippos, a baby crocodile, and dozens of different species of birds!

A green lizard clings to a tree
I had the opportunity to explore the scenic areas that surround Bugoye

My time in Uganda has not only been defined by the invaluable work on the severe malaria study but also by these unforgettable encounters with the country’s natural wonders. These experiences have provided me with a profound appreciation for the remarkable diversity and beauty of Uganda’s landscapes and wildlife, making my journey a truly transformative one. I’m looking forward to using this experience to influence my Public Health career in the future.

-Jennifer

Reflections on My Summer Practicum with The UNC Water Institute

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It has been a few weeks since my practicum ended with the UNC Water Institute. I am grateful that I was given this opportunity to explore the field of water and sanitation hygiene (WASH) in health care facilities (HCFs) and was able to connect with several organizations and WASH professionals during the practicum.

The key activities that I completed during this practicum included a grey literature sorting, systematic reviews of documents and document extractions, nine interviews (11 participants) of international WASH in healthcare facility professionals, and an analysis of the washinhcf.org website. These activities guided my practicum products, which included a mini study and report of the washinhcf.org website, and a compilation of WASHFIT modules on sanitation related studies.

One of the most interesting parts of the practicum were the interviews. The interviews conducted were to find out training and capacity development needs in HCFs internationally, and questions asked in the interview were based on the eight practical steps identified by the WHO and UNICEF to reach universal access to WaSH in healthcare facilities, such as conducting situation assessments, establishing national standards, implementing infrastructure, and monitoring. I found that many HCFs, with the support of local and national governments had accomplished situational assessments and established at least a national standard, with some HCFs developing individual standards for HCFs or within a specific community. A large barrier to moving forward with implementation, monitoring, and community engagement were resources available to be allocated to hardware and software needs. As the WASH sector grows and the need for services becomes more apparent, resources will need to be prioritized in such a way that they sustain HCF abilities to carry through the eight practical steps.

These interviews also shaped our practicum team’s perception of what tools and guidelines are necessary for advancing services in several domains of WASH and helped us create the WASHFIT modules. The modules included a summary of an intervention or study, the findings and outcomes, and any other information that was important to note about the intervention. The modules also included a visual of where each intervention was conducted, the details of the area, which included type of healthcare facility, geographic makeup (urban or rural), and included icons to symbolize what WASH components were included in the intervention. Once published and shared, WASH professionals may use these modules to guide interventions in their own HCFs and advance within the eight practical steps.

-Anushka