GWAS COGENT-BP

GWAS COGENT-BP

These are results from COGENT-BP meta-analyses from Liang et al 2017 Plos Genetics which includes only AA and Africans

Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.
Liang J, Le TH, Edwards DRV, Tayo BO, Gaulton KJ, Smith JA, Lu Y, Jensen RA, Chen G, Yanek LR, Schwander K, Tajuddin SM, Sofer T, Kim W, Kayima J, McKenzie CA, Fox E, Nalls MA, Young JH, Sun YV, Lane JM, Cechova S, Zhou J, Tang H, Fornage M, Musani SK, Wang H, Lee J, Adeyemo A, Dreisbach AW, Forrester T, Chu PL, Cappola A, Evans MK, Morrison AC, Martin LW, Wiggins KL, Hui Q, Zhao W, Jackson RD, Ware EB, Faul JD, Reiner AP, Bray M, Denny JC, Mosley TH, Palmas W, Guo X, Papanicolaou GJ, Penman AD, Polak JF, Rice K, Taylor KD, Boerwinkle E, Bottinger EP, Liu K, Risch N, Hunt SC, Kooperberg C, Zonderman AB, Laurie CC, Becker DM, Cai J, Loos RJF, Psaty BM, Weir DR, Kardia SLR, Arnett DK, Won S, Edwards TL, Redline S, Cooper RS, Rao DC, Rotter JI, Rotimi C, Levy D, Chakravarti A, Zhu X, Franceschini N. PLoS Genet. 2017 May 12;13(5):e1006728. doi: 10.1371/journal.pgen.1006728. eCollection 2017 May. PMID: 28498854

Each file is one different blood pressure trait: PP (pulse pressure), DBP (diastolic blood pressure), SBP (systolic blood pressure), HTN (hypertension) so keep them separate.

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GWAS_COGENT_BP Adds 4 .csv files Access .tar.gz (88 files, total 1.72 GB)

Data Header Descriptions

pos Chromosome position (hg19)
chr Chromosome
A1 Effect allele
A2 Other allele
freq Allele frequency of A1
effect Beta values for A1 allele
se Standard error of beta
pvalue P-value
N Total number
ID rsnumber